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These inhibitors bind to the enzymes active site, effectively blocking its activity

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doi:10.1046/j.1467-2494.2000.00025.x

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If approved, CagriSema would provide patients and healthcare professionals with an additional treatment option supported by results from the REDEFINE clinical program, including robust efficacy, high treatment completion rates, and a tolerability profile consistent with its underlying pharmacology

The central mechanism involves both homeostatic (energy balance) and hedonic (food reward) pathways, providing comprehensive appetite regulation